Involved in the activation cascade of caspases responsible for apoptosis execution (By similarity). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Loss of zygotic DCP-1 function causes larval lethality and melanotic tumors.
Protein type: Apoptosis; EC 18.104.22.168; Endoplasmic reticulum; Mitochondrial; Protease
Cellular Component: cytosol; mitochondrion
Molecular Function: cysteine-type endopeptidase activity; protein binding
Biological Process: actin filament organization; apoptosis; autophagic cell death; cellular response to starvation; cytoplasmic transport, nurse cell to oocyte; multicellular organismal development; neuron remodeling; nurse cell apoptosis; oogenesis; ovarian nurse cell to oocyte transport; positive regulation of autophagy; positive regulation of macroautophagy; programmed cell death; salivary gland cell autophagic cell death