Involved in the activation cascade of caspases responsible for apoptosis execution (By similarity). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Loss of zygotic DCP-1 function causes larval lethality and melanotic tumors.
Protein type: Endoplasmic reticulum; EC 18.104.22.168; Protease; Apoptosis; Mitochondrial
Cellular Component: cytosol; mitochondrion
Molecular Function: cysteine-type endopeptidase activity; protein binding
Biological Process: actin filament organization; apoptosis; autophagic cell death; cellular response to starvation; cytoplasmic transport, nurse cell to oocyte; multicellular organismal development; neuron remodeling; nurse cell apoptosis; oogenesis; ovarian nurse cell to oocyte transport; positive regulation of autophagy; positive regulation of macroautophagy; programmed cell death; salivary gland cell autophagic cell death
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.