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Protein Page:
LIG1 (mouse)

Overview
LIG1 is an enzyme that functions in DNA replication and the base excision repair process. Mutations leading to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage; EC 6.5.1.1; Ligase
Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; mitochondrion; nucleoplasm; nucleus
Molecular Function: DNA ligase (ATP) activity; DNA ligase activity
Biological Process: base-excision repair; DNA repair; DNA replication; double-strand break repair via nonhomologous end joining; response to hydrogen peroxide
Reference #:  P37913 (UniProtKB)
Alt. Names/Synonyms: AL033288; DNA ligase 1; DNA ligase I; DNLI1; Lig-1; Lig1; ligase I, DNA, ATP-dependent; LigI; Polydeoxyribonucleotide synthase [ATP] 1
Gene Symbols: Lig1
Molecular weight: 102,290 Da
Basal Isoelectric point: 6.43  Predict pI for various phosphorylation states
Select Structure to View Below

LIG1

Protein Structure Not Found.
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