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Protein Page:
CHD-2 (human)

Overview
CHD-2 Sequence-selective DNA-binding protein. Belongs to the SNF2/RAD54 helicase family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; EC 3.6.4.12; Helicase
Chromosomal Location of Human Ortholog: 15q26
Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus
Molecular Function: ATP-dependent DNA helicase activity; DNA binding; histone binding
Biological Process: muscle development; regulation of transcription from RNA polymerase II promoter
Disease: Epileptic Encephalopathy, Childhood-onset
Reference #:  O14647 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent helicase CHD2; CHD-2; CHD2; chromodomain helicase DNA binding protein 2; Chromodomain-helicase-DNA-binding protein 2; DKFZp547I1315; DKFZp686E01200; DKFZp781D1727; FLJ38614
Gene Symbols: CHD2
Molecular weight: 211,344 Da
Basal Isoelectric point: 8.22  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

CHD-2

Protein Structure Not Found.


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