Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. Belongs to the synaptobrevin family. Note: This description may include information from UniProtKB.
Protein type: Vesicle; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2p12-p11.2
Cellular Component: cytoplasm; cytosol; early endosome; early endosome membrane; integral to membrane; late endosome membrane; lysosomal membrane; membrane; perinuclear region of cytoplasm; plasma membrane; recycling endosome; secretory granule membrane; SNARE complex; vesicle
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.