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Protein Page:
TNFSF15 (human)

Overview
TNFSF15 Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. Belongs to the tumor necrosis factor family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Cytokine; Membrane protein, integral
Chromosomal Location of Human Ortholog: 9q32
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: receptor binding
Biological Process: activation of NF-kappaB-inducing kinase; caspase activation; cytokine metabolic process; tumor necrosis factor-mediated signaling pathway
Reference #:  O95150 (UniProtKB)
Alt. Names/Synonyms: TL1; TL1A; tumor necrosis factor (ligand) superfamily, member 15; VEGI; VEGI192A
Gene Symbols: TNFSF15
Molecular weight: 28,087 Da
Basal Isoelectric point: 6.31  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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TNFSF15

Protein Structure Not Found.
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