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Protein Page:
FLT3LG (human)

Overview
FLT3LG Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Membrane protein, integral; Ligand, receptor tyrosine kinase
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: extracellular region; extracellular space; integral to membrane; membrane
Molecular Function: cytokine activity; protein homodimerization activity; receptor binding; receptor tyrosine kinase binding
Biological Process: embryonic hemopoiesis; homeostasis of number of cells within a tissue; lymphocyte differentiation; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of myoblast differentiation; positive regulation of natural killer cell differentiation; positive regulation of protein amino acid phosphorylation; positive regulation of transcription from RNA polymerase II promoter; regulation of myeloid dendritic cell activation; signal transduction
Reference #:  P49771 (UniProtKB)
Gene Symbols: FLT3LG
Molecular weight: 26,416 Da
Basal Isoelectric point: 7.6  Predict pI for various phosphorylation states
Select Structure to View Below

FLT3LG

Protein Structure Not Found.
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Modification Sites and Domains  

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