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Protein Page:
SNCB (human)

Overview
SNCB a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May play a role in neuronal plasticity, is abundant in neurofibrillary lesions of Alzheimer's patients. Highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 5q35
Cellular Component: cytoplasm; Golgi apparatus; inclusion body; nucleoplasm
Molecular Function: calcium ion binding; phospholipase inhibitor activity
Disease: Dementia, Lewy Body
Reference #:  Q16143 (UniProtKB)
Alt. Names/Synonyms: Beta-synuclein; SNCB; synuclein, beta; SYUB
Gene Symbols: SNCB
Molecular weight: 14,288 Da
Basal Isoelectric point: 4.41  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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SNCB

Protein Structure Not Found.


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