Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
Epigen (human)

Epigen Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. 7 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Ligand, receptor tyrosine kinase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular space; integral to plasma membrane
Molecular Function: epidermal growth factor receptor binding; growth factor activity
Biological Process: activation of MAPK activity; angiogenesis; positive regulation of cell proliferation; positive regulation of epidermal growth factor receptor activity; positive regulation of epithelial cell proliferation; positive regulation of MAP kinase activity; positive regulation of mitosis
Reference #:  Q6UW88 (UniProtKB)
Alt. Names/Synonyms: EPG; EPGN; epigen; epithelial mitogen homolog
Gene Symbols: EPGN
Molecular weight: 17,091 Da
Basal Isoelectric point: 6.5  Predict pI for various phosphorylation states
CST Pathways:  ErbB/HER Signaling
Select Structure to View Below


Protein Structure Not Found.

STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene