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Protein Page:
WIF1 (human)

Overview
WIF1 Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Inhibitor; Secreted
Chromosomal Location of Human Ortholog: 12q14.3
Cellular Component: extracellular region
Molecular Function: protein binding
Biological Process: multicellular organismal development; positive regulation of fat cell differentiation; signal transduction; Wnt receptor signaling pathway
Reference #:  Q9Y5W5 (UniProtKB)
Alt. Names/Synonyms: WIF-1; WIF1; WNT inhibitory factor 1
Gene Symbols: WIF1
Molecular weight: 41,528 Da
Basal Isoelectric point: 7.84  Predict pI for various phosphorylation states
CST Pathways:  Wnt/ß-Catenin Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

WIF1

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T215‑p HCEKALCtPRCMNGG
0 1 T255‑p TTCFNGGtCFYPGKC
  mouse

 
I215 HCEKALCIPRCMNGG
T255 TTCFNGGTCFYPGKC
  rat

 
I215 HCEKALCIPRCMNGG
T255 ATCFNGGTCFYPGKC
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