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Protein Page:
RECQL (human)

Overview
RECQL DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Interacts with EXO1 and MLH1. High expression in heart, lung, skeletal muscle and kidney, low expression in brain. Belongs to the helicase family. RecQ subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage; EC 3.6.4.12; Helicase
Chromosomal Location of Human Ortholog: 12p12
Cellular Component: chromosome; cytoplasm; membrane; nucleoplasm; nucleus
Molecular Function: ATP-dependent 3'-5' DNA helicase activity; ATP-dependent DNA helicase activity; DNA binding; DNA helicase activity; four-way junction helicase activity; protein binding
Biological Process: DNA repair; DNA strand renaturation; double-strand break repair via homologous recombination
Reference #:  P46063 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent DNA helicase Q1; DNA helicase Q1-like; DNA helicase, RecQ-like type 1; DNA-dependent ATPase Q1; RecQ protein-like; RecQ protein-like (DNA helicase Q1-like); RecQ protein-like 1; RECQ1; RECQL; RECQL1
Gene Symbols: RECQL
Molecular weight: 73,457 Da
Basal Isoelectric point: 8.13  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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RECQL

Protein Structure Not Found.
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