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Protein Page:
LRIG1 (human)

Overview
LRIG1 a singhle-pass type I membrane protein that acts as a feedback negative regulator of signaling by receptor tyrosine kinases. Regulates cadherin-dependent contact inhibition. Interacts with EGFR, HER2, -3, and -4. Two isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Protein kinase, regulatory subunit
Chromosomal Location of Human Ortholog: 3p14
Reference #:  Q96JA1 (UniProtKB)
Alt. Names/Synonyms: DKFZp586O1624; leucine-rich repeat protein LRIG1; leucine-rich repeats and immunoglobulin-like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; LIG1; LRIG1; ortholog of mouse integral membrane glycoprotein LIG-1
Gene Symbols: LRIG1
Molecular weight: 119,113 Da
Basal Isoelectric point: 6.66  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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LRIG1

Protein Structure Not Found.
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