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Protein Page:
PDLIM2 (human)

PDLIM2 Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. Interacts with alpha-actinins ACTN1 and ACTN4, FLNA and MYH9. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 8p21.3
Cellular Component: actin cytoskeleton; focal adhesion
Reference #:  Q96JY6 (UniProtKB)
Alt. Names/Synonyms: FLJ34715; MYSTIQUE; PDLI2; PDLIM2; PDZ and LIM domain 2 (mystique); PDZ and LIM domain protein 2; PDZ-LIM protein mystique; SLIM
Gene Symbols: PDLIM2
Molecular weight: 37,459 Da
Basal Isoelectric point: Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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