Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
SAG (human)

SAG Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated- phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Retina and pineal gland. Belongs to the arrestin family. Note: This description may include information from UniProtKB.
Protein type: G protein regulator, misc.; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: cytosol
Molecular Function: protein phosphatase inhibitor activity
Biological Process: cell surface receptor linked signal transduction; regulation of rhodopsin mediated signaling; rhodopsin mediated signaling
Disease: Oguchi Disease 1; Retinitis Pigmentosa 47
Reference #:  P10523 (UniProtKB)
Alt. Names/Synonyms: 48 kDa protein; arrestin 1; ARRS; DKFZp686D1084; DKFZp686I1383; retina and pineal gland (arrestin); Retinal S-antigen; retinal S-antigen (48 KDa protein); Rod photoreceptor arrestin; RP47; S-AG; S-antigen; S-arrestin; SAG
Gene Symbols: SAG
Molecular weight: 45,120 Da
Basal Isoelectric point: 6.14  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script

STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene