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Protein Page:
ATG9A (human)
rdtyret
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
ATG9A Plays a role in autophagy. Cycles between a juxta- nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and FAM48A. Interacts with FAM48A. Belongs to the ATG9 family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Autophagy; Membrane protein, multi-pass; Vesicle; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q35
Cellular Component: cytoplasmic vesicle; endoplasmic reticulum membrane; endosome; integral to membrane; late endosome; late endosome membrane; membrane; recycling endosome; trans-Golgi network
Molecular Function: protein binding
Biological Process: autophagic vacuole formation; innate immune response; mitochondrion degradation; negative regulation of interferon-beta production; protein localization in Golgi apparatus; protein transport
Reference #:  Q7Z3C6 (UniProtKB)
Alt. Names/Synonyms: APG9 autophagy 9-like 1; APG9-like 1; APG9L1; ATG9 autophagy related 9 homolog A (S. cerevisiae); ATG9A; autophagy 9-like 1 protein; Autophagy-related protein 9A; MGD3208
Gene Symbols: ATG9A
Molecular weight: 94,447 Da
Basal Isoelectric point: 6.19  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

ATG9A

Protein Structure Not Found.


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Sites Implicated In
autophagy, induced: S761‑p
molecular association, regulation: S761‑p

Modification Sites and Domains  
Click here to view other types of protein modifications

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 25 S14‑p EYQRLEAsysDsPPG
0 5 Y15‑p YQRLEAsysDsPPGE
0 3 S16‑p QRLEAsysDsPPGEE
0 17 S18‑p LEAsysDsPPGEEDL
0 4 Y209‑p ELTELDIyHRILRFQ
0 1 K225‑ub YMVALVNkSLLPLRF
0 1 S543‑p SAGQTEAsVyQQAED
0 1 Y545‑p GQTEAsVyQQAEDGK
0 1 S556‑p EDGKTELsLMHFAIT
0 4 K581‑ub TAFLGFLkEQVQRDG
0 1 S642‑p LPRDLQGsRHRAEVA
0 1 S650‑p RHRAEVAsALRsFsP
0 1 S654‑p EVAsALRsFsPLQPG
1 14 S656‑p AsALRsFsPLQPGQA
0 4 S675‑p AHSTMTGsGVDARTA
0 51 S735‑p HVWHRREsDEsGEsA
0 25 S738‑p HRREsDEsGEsAPDE
0 20 S741‑p EsDEsGEsAPDEGGE
0 1 S755‑p EGARAPQsIPRsAsY
0 8 S759‑p APQsIPRsAsYPCAA
1 17 S761‑p QsIPRsAsYPCAAPR
0 1 A766 sAsYPCAAPRPGAPE
0 2 Y785‑p HGGFQRRyGGITDPG
0 1 S799‑p GTVPRVPsHFSRLPL
0 63 S828‑p EPVPEEGsEDELPPQ
  mouse

► Hide Isoforms
 
S14‑p EYQRLEAsYSDsPPG
Y15 YQRLEAsYSDsPPGE
S16 QRLEAsYSDsPPGEE
S18‑p LEAsYSDsPPGEEDL
Y209 ELTELDIYHRILRFQ
K225 YMVALVNKSLLPLRF
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  ATG9A iso2  
S14‑p EYQRLEAsYsDsPPG
Y15 YQRLEAsYsDsPPGE
S16‑p QRLEAsYsDsPPGEE
S18‑p LEAsYsDsPPGEEDL
Y209 ELTELDIYHRILRFQ
K225 YMVALVNKSLLPLRF
S543 SGGQTEASVYQQAED
Y545 GQTEASVYQQAEDGK
S556 EDGKTELSLMHFAIT
K581‑ub TAFLGFLkEQVQRDG
S642 LSRDLQGSRHRADVA
S650 RHRADVASALRSFsP
S654 DVASALRSFsPLQPG
S656‑p ASALRSFsPLQPGAA
S675‑p VPSTMTGsGVDARTA
S735‑p HVWHRREsDEsGEsA
S738‑p HRREsDEsGEsAPEE
S741‑p EsDEsGEsAPEEGGE
P755 EGARAPQPIPRsAsY
S759‑p APQPIPRsAsYPCAt
S761‑p QPIPRsAsYPCAtPR
T766‑p sAsYPCAtPRPGAPE
Y785 HGGFQRRYGGITDPG
S799 GTVPRGPSHFSRLPL
S828‑p EPVPEEGsEDELPPQ
  rat

 
S14 EYQRLEASYsDsPPG
Y15 YQRLEASYsDsPPGE
S16‑p QRLEASYsDsPPGEE
S18‑p LEASYsDsPPGEEDL
Y209 ELTELDIYHRILRFQ
K225 YMVALVNKSLLPLRF
S543 SGGQTEASVYQQAED
Y545 GQTEASVYQQAEDGK
S556 EDGKTELSLMHFAIT
K581 TAFLGFLKEQVQRDG
S642 LSRDLQGSRHRADVA
S650 RHRADVASALRSFsP
S654 DVASALRSFsPLQPG
S656‑p ASALRSFsPLQPGQA
S675 VPSTMTGSGVDARTA
S735‑p HVWHRREsDEsGEsA
S738‑p HRREsDEsGEsAPEE
S741‑p EsDEsGEsAPEEGGE
P755 EGARAPQPIPRSASY
S759 APQPIPRSASYPCAT
S761 QPIPRSASYPCATPR
T766 SASYPCATPRPGAPE
Y785 HGGFQRRYGGITDPG
S799 GTVPRAPSHFSRLPL
S828‑p EPVPEEGsEDELPPQ
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