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Protein Page:
CHKA (human)

CHKA Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. Belongs to the choline/ethanolamine kinase family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC; EC; Kinase, other; Lipid Metabolism - glycerophospholipid
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: cytosol
Molecular Function: choline kinase activity; drug binding; ethanolamine kinase activity; signal transducer activity
Biological Process: lipid metabolic process; lipid transport; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process
Reference #:  P35790 (UniProtKB)
Alt. Names/Synonyms: CHETK-alpha; CHK; CHKA; Choline kinase alpha; CK; CKI; EK; Ethanolamine kinase
Gene Symbols: CHKA
Molecular weight: 52,249 Da
Basal Isoelectric point: 6.16  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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