a major structural protein of the eye lens. A member of the small heat shock protein (sHSP also known as the HSP20) family. Alpha-B is expressed in the lens as well as other tissues. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Note: This description may include information from UniProtKB.
Molecular Function: identical protein binding; protein binding; protein homodimerization activity; unfolded protein binding
Biological Process: muscle contraction; negative regulation of apoptosis; negative regulation of intracellular transport; negative regulation of protein homooligomerization; protein homooligomerization; protein stabilization