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Protein Page:
K6c (human)

K6c Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq, Jul 2009]
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: cytosol
Molecular Function: protein binding
Biological Process: intermediate filament cytoskeleton organization and biogenesis; keratinization
Disease: Palmoplantar Keratoderma, Nonepidermolytic, Focal Or Diffuse
Reference #:  P48668 (UniProtKB)
Alt. Names/Synonyms: CK-6C; CK-6E; Cytokeratin-6C; Cytokeratin-6E; K2C6C; K6C; K6E; keratin 6C; keratin 6E; Keratin K6h; Keratin, type II cytoskeletal 6C; Keratin-6C; KRT6C; KRT6E; MGC102925; MGC163455; MGC163457; Type-II keratin Kb12
Gene Symbols: KRT6C
Molecular weight: 60,025 Da
Basal Isoelectric point: 8.09  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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