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Protein Page:
Myb (human)

Overview
Myb Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. 6 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 6q22-q23
Cellular Component: nucleus
Molecular Function: protein binding
Biological Process: chromatin remodeling; mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of histone H3-K4 methylation; positive regulation of histone H3-K9 methylation; positive regulation of T-helper cell differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent
Reference #:  P10242 (UniProtKB)
Alt. Names/Synonyms: c-myb; c-myb protein (140 AA); c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; c-myb_CDS; Cmyb; efg; MYB; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb myeloblastosis viral oncogene homolog (avian)
Gene Symbols: MYB
Molecular weight: 72,341 Da
Basal Isoelectric point: 6.35  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Myb

Protein Structure Not Found.
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