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Protein Page:
BLK (human)

Overview
BLK a nonreceptor tyrosine kinase of the Src family. Expressed predominantly in B lymphocytes Note: This description may include information from UniProtKB.
Protein type: EC 2.7.10.2; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); Src family; TK group
Chromosomal Location of Human Ortholog: 8p23-p22
Cellular Component: extrinsic to internal side of plasma membrane
Molecular Function: non-membrane spanning protein tyrosine kinase activity; protein binding; protein-tyrosine kinase activity; receptor binding
Biological Process: B cell receptor signaling pathway; cell differentiation; cytoskeleton organization and biogenesis; innate immune response; negative regulation of apoptosis; positive regulation of insulin secretion; regulation of cell proliferation; regulation of phagocytosis; transmembrane receptor protein tyrosine kinase signaling pathway
Disease: Maturity-onset Diabetes Of The Young, Type 11
Reference #:  P51451 (UniProtKB)
Alt. Names/Synonyms: B lymphocyte kinase; B lymphoid tyrosine kinase; BLK; BLK nonreceptor tyrosine kinase; MGC10442; p55-Blk; Tyrosine-protein kinase Blk
Gene Symbols: BLK
Molecular weight: 57,706 Da
Basal Isoelectric point: 7.98  Predict pI for various phosphorylation states
CST Pathways:  GPCR Signaling to MAPKs  |  Tyrosine Kinases & Substrates
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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BLK

Protein Structure Not Found.
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