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Protein Page:
SEMA4B iso3 (human)

Overview
SEMA4B iso3 a single-pass type I membrane protein that inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. Two alternatively spliced human isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: 15q25
Cellular Component: extracellular space; plasma membrane
Molecular Function: chemorepellent activity; semaphorin receptor binding
Biological Process: negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration
Reference #:  J3KNP4 (UniProtKB)
Alt. Names/Synonyms: KIAA1745; MGC131831; SEM4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B; SEMA4B; SEMAC; Semaphorin-4B; SemC
Gene Symbols: SEMA4B
Molecular weight: 92,766 Da
Basal Isoelectric point: 6.64  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SEMA4B iso3

Protein Structure Not Found.


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