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Protein Page:
NFM (human)

NFM a neurofilament intermediate filament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The levels of phosphorylation are altered developmentally and coincident with a change in the neurofilament function. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 8p21
Cellular Component: axon
Molecular Function: microtubule binding; structural constituent of cytoskeleton
Biological Process: neurofilament bundle assembly
Reference #:  P07197 (UniProtKB)
Alt. Names/Synonyms: 160 kDa neurofilament protein; NEF3; NEFM; Neurofilament 3; Neurofilament medium polypeptide; Neurofilament triplet M protein; neurofilament, medium polypeptide; neurofilament, medium polypeptide 150kDa; neurofilament-3 (150 kD medium); NF-M; NFM
Gene Symbols: NEFM
Molecular weight: 102,472 Da
Basal Isoelectric point: 4.9  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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