Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation. By growth factors. Belongs to the EGR C2H2-type zinc-finger protein family. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding
Molecular Function: DNA binding; histone acetyltransferase binding; metal ion binding; protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: BMP signaling pathway; cytokine and chemokine mediated signaling pathway; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of apoptosis; regulation of protein sumoylation; response to glucose stimulus; response to insulin stimulus; T cell differentiation; transcription from RNA polymerase II promoter
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.