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Protein Page:
EVL (mouse)

EVL Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. Required to transform actin polymerization into active movement for the propulsive force of Listeria monocytogenes. Belongs to the Ena/VASP family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12|12 F1
Cellular Component: cytoplasm; focal adhesion; lamellipodium; membrane
Molecular Function: profilin binding; protein binding; SH3 domain binding
Biological Process: actin polymerization and/or depolymerization; positive regulation of actin filament polymerization; positive regulation of stress fiber formation
Reference #:  P70429 (UniProtKB)
Alt. Names/Synonyms: AI528774; Ena-vasodilator stimulated phosphoprotein; Ena/vasodilator-stimulated phosphoprotein-like; Ena/VASP-like protein; Evl
Gene Symbols: Evl
Molecular weight: 44,337 Da
Basal Isoelectric point: 8.92  Predict pI for various phosphorylation states
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Protein Structure Not Found.
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