Involved in intracellular vesicle trafficking. Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3. Interacts with GOPC. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A. Belongs to the syntaxin family. Note: This description may include information from UniProtKB.
Cellular Component: clathrin-coated vesicle; early endosome; Golgi apparatus; integral to membrane; perinuclear region of cytoplasm; phagocytic vesicle; plasma membrane; SNARE complex; terminal button; trans-Golgi network; trans-Golgi network membrane
Molecular Function: protein binding; SNAP receptor activity; syntaxin binding
Biological Process: endosome organization and biogenesis; Golgi vesicle transport; intracellular protein transport; regulation of protein localization; retrograde transport, endosome to Golgi; vesicle docking; vesicle fusion
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.