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Protein Page:
DAP (human)

Overview
DAP a 15 kDa, proline rich protein that possesses one SH3 binding motif. Negatively regulates autophagy and is involved in mediating interferon-gamma-induced cell death. Localizes in the cytoplasm, but the detailed mechanism of its proapoptotic function is unclear. Note: This description may include information from UniProtKB.
Protein type: Autophagy
Chromosomal Location of Human Ortholog: 5p15.2
Biological Process: apoptosis; caspase activation; cellular response to amino acid starvation; inhibition of NF-kappaB transcription factor; negative regulation of autophagy; negative regulation of transcription, DNA-dependent
Reference #:  P51397 (UniProtKB)
Alt. Names/Synonyms: DAP; DAP-1; DAP1; death-associated protein; Death-associated protein 1; MGC99796
Gene Symbols: DAP
Molecular weight: 11,165 Da
Basal Isoelectric point: 9.3  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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DAP

Protein Structure Not Found.


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