Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Belongs to the WD repeat L(2)GL family. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Cytoskeletal; Motility/polarity/chemotaxis
Molecular Function: GTPase activator activity; protein binding; protein kinase binding; Rab GTPase binding; structural molecule activity; syntaxin binding
Biological Process: axonogenesis; cortical actin cytoskeleton organization and biogenesis; Golgi to plasma membrane transport; protein complex assembly; regulation of exocytosis; regulation of protein secretion