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Protein Page:
NRP2 (human)

Overview
NRP2 High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc.
Chromosomal Location of Human Ortholog: 2q33.3
Cellular Component: membrane; plasma membrane
Molecular Function: growth factor binding; receptor activity
Biological Process: axon extension involved in axon guidance; nerve development; positive regulation of endothelial cell proliferation; vascular endothelial growth factor receptor signaling pathway
Reference #:  O60462 (UniProtKB)
Alt. Names/Synonyms: MGC126574; neuropilin 2; Neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); NP2; NPN2; NRP2; PRO2714; receptor for VEGF165 and semaphorins class3; Vascular endothelial cell growth factor 165 receptor 2; vascular endothelial growth factor-165 receptor 2; VEGF165R2
Gene Symbols: NRP2
Molecular weight: 104,859 Da
Basal Isoelectric point: 5.04  Predict pI for various phosphorylation states
Select Structure to View Below

NRP2

Protein Structure Not Found.
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