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Protein Page:
TBX21 (human)

Overview
TBX21 Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. T-cell specific. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 17q21.32
Molecular Function: transcription factor activity
Biological Process: multicellular organismal development; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; response to virus
Disease: Asthma, Nasal Polyps, And Aspirin Intolerance
Reference #:  Q9UL17 (UniProtKB)
Alt. Names/Synonyms: T-bet; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; TBET; TBLYM; TBX21; Transcription factor TBLYM
Gene Symbols: TBX21
Molecular weight: 58,328 Da
Basal Isoelectric point: 5.67  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

TBX21

Protein Structure Not Found.


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