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Protein Page:
HNRPLL (human)

HNRPLL RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. Interacts with HNRNPL. Up-regulated in stimulated T-cells. Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 2p22.1
Cellular Component: membrane
Molecular Function: mRNA binding; protein binding
Biological Process: positive regulation of RNA splicing
Reference #:  Q8WVV9 (UniProtKB)
Alt. Names/Synonyms: Heterogeneous nuclear ribonucleoprotein L-like; HNRLL; hnRNPLL; HNRPLL; SRRF; stromal RNA regulating factor; Stromal RNA-regulating factor
Gene Symbols: HNRNPLL
Molecular weight: 60,083 Da
Basal Isoelectric point: 7.83  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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