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Protein Page:
RAB10 (human)
rdtyret
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
RAB10 a protein of the GTPase superfamily, Rab family. May be involved in vesicular trafficking and neurotransmitter release. Localized to the inner face of the cell membrane by a lipid-anchor. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 2p23.3
Cellular Component: cytoplasmic vesicle membrane; endoplasmic reticulum membrane; endosome; exocyst; focal adhesion; Golgi apparatus; Golgi membrane; perinuclear region of cytoplasm; phagocytic vesicle membrane; plasma membrane; recycling endosome; recycling endosome membrane; trans-Golgi network
Molecular Function: GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding
Biological Process: antigen processing and presentation; axonogenesis; cellular response to insulin stimulus; endosome transport; establishment of neuroblast polarity; Golgi to plasma membrane protein transport; Golgi to plasma membrane transport; polarized epithelial cell differentiation; small GTPase mediated signal transduction; vesicle-mediated transport
Reference #:  P61026 (UniProtKB)
Alt. Names/Synonyms: GTP-binding protein RAB10; RAB10; RAB10, member RAS oncogene family; ras-related GTP-binding protein; Ras-related protein Rab-10
Gene Symbols: RAB10
Molecular weight: 22,541 Da
Basal Isoelectric point: 8.58  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

RAB10

Protein Structure Not Found.


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Modification Sites and Domains  
Click here to view other types of protein modifications

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 T5‑p ___MAKKtyDLLFKL
0 49 Y6‑p __MAKKtyDLLFKLL
0 2 S18‑p KLLLIGDsGVGKTCV
0 1 T41‑p FNTTFIStIGIDFKI
0 1 K59 ELQGKKIKLQIWDTA
0 20 T73‑p AGQERFHtITTsYYR
0 1 S77‑p RFHtITTsYYRGAMG
0 3 K102‑ac KSFENISkWLRNIDE
0 6 K102‑ub KSFENISkWLRNIDE
0 1 K129 NKCDMDDKRVVPKGK
0 3 K154‑ub RFFETSAkANINIEK
0 2 T174‑p AEDILRKtPVkEPNs
0 2 K177‑ub ILRKtPVkEPNsENV
0 2 S181‑p tPVkEPNsENVDIss
0 2 S187‑p NsENVDIssGGGVTG
0 2 S188‑p sENVDIssGGGVTGW
0 1 K196‑ac GGGVTGWkSKCC___
  mouse

 
T5 ___MAKKTyDLLFKL
Y6‑p __MAKKTyDLLFKLL
S18‑p KLLLIGDsGVGKTCV
T41 FNTTFISTIGIDFKI
K59 ELQGKKIKLQIWDTA
T73‑p AGQERFHtITTSYYR
S77 RFHtITTSYYRGAMG
K102 KSFENISKWLRNIDE
K102‑ub KSFENISkWLRNIDE
K129‑ac NKCDMDDkRVVPKGK
K154‑ub RFFETSAkANINIEK
T174 AEDILRKTPVkEPNS
K177‑ub ILRKTPVkEPNSENV
S181 TPVkEPNSENVDISs
S187 NSENVDISsGGGVTG
S188‑p SENVDISsGGGVTGW
K196 GGGVTGWKSKCC___
  rat

 
T5 ___MAKKTyDLLFKL
Y6‑p __MAKKTyDLLFKLL
S18 KLLLIGDSGVGKTCV
T41 FNTTFISTIEIDFKI
K59‑ub ELQGKKIkLQIWDTA
T73 AGQERFHTITTSYYR
S77 RFHTITTSYYRGAMG
K102‑ac KSFENISkWLRNIDQ
K102 KSFENISKWLRNIDQ
K129 NKCDMDHKRVVPKGK
K154 RFFETSAKANINIEK
T174 PEDILRKTPVKEPNS
K177 ILRKTPVKEPNSENV
S181 TPVKEPNSENVDISS
S187 NSENVDISSGGGVTG
S188 SENVDISSGGGVTGW
K196 GGGVTGWKSKCC___
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