May be involved in vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization. Interacts with MAP4K2 and SYTL4. Interacts with SGSM1 and SGSM3. Interacts with OPTN. Interacts with RAB3IP. Interacts with MYO5B. Interacts with PIFO/C1orf88. Interacts with BIRC6/bruce. Interacts with OCRL. Belongs to the small GTPase superfamily. Rab family. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric, Rab; Motility/polarity/chemotaxis; Oncoprotein; G protein, monomeric
Molecular Function: GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding; protein kinase binding; Rab GTPase binding
Biological Process: axonogenesis; cellular response to insulin stimulus; cilium biogenesis; G2/M transition of mitotic cell cycle; Golgi vesicle fusion to target membrane; mitotic cell cycle; organelle organization and biogenesis; protein secretion; regulation of long-term neuronal synaptic plasticity; regulation of protein transport; small GTPase mediated signal transduction; vesicle docking during exocytosis
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.