Curated Information
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Curated Information Page
PubMed Id: 17163454 
Storch B, Meixlsperger S, Jumaa H (2007) The Ig-alpha ITAM is required for efficient differentiation but not proliferation of pre-B cells. Eur J Immunol 37, 252-60 17163454
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Information from this record has been curated, but not yet edited in PhosphoSitePlus® and may be incomplete.
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Y176-p - Ig-alpha (mouse)
Orthologous residues
Ig‑alpha (human): Y182‑p, Ig‑alpha (mouse): Y176‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  B lymphocyte
 Cellular systems studied:  primary cells
 Species studied:  mouse

Y182-p - Ig-alpha (mouse)
Orthologous residues
Ig‑alpha (human): Y188‑p, Ig‑alpha (mouse): Y182‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  B lymphocyte
 Cellular systems studied:  primary cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (function):  activity, induced
 Effect of modification (process):  cell differentiation, altered
 Comments:  Ca(2+) signaling

Y193-p - Ig-alpha (mouse)
Orthologous residues
Ig‑alpha (human): Y199‑p, Ig‑alpha (mouse): Y193‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  B lymphocyte
 Cellular systems studied:  primary cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (function):  activity, induced
 Effect of modification (process):  cell differentiation, altered
 Comments:  Ca(2+) signaling

Y204-p - Ig-alpha (mouse)
Orthologous residues
Ig‑alpha (human): Y210‑p, Ig‑alpha (mouse): Y204‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  B lymphocyte
 Cellular systems studied:  primary cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (function):  activity, induced
 Effect of modification (process):  cell differentiation, altered
 Comments:  Ca(2+) signaling


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