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Orthologous residues
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ZO1 (human): S168‑p, ZO1 iso2 (human): S168‑p, ZO1 (mouse): S168‑p, ZO1 iso2 (mouse): S168‑p, ZO1 (rat): S156‑p
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Characterization
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|
Methods used to characterize site in vivo:
mutation of modification site, western blotting
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|
Disease tissue studied:
lung cancer, non-small cell lung cancer
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|
Relevant cell lines - cell types - tissues:
NCI-H460 (pulmonary)
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Cellular systems studied:
cell lines
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|
Species studied:
human
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Downstream Regulation
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Effect of modification (function):
intracellular localization, molecular association, regulation
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Modification regulates interactions with:
|
|
Interacting molecule
|
Interacting domains
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Effect
|
Consequences (function)
|
Consequences (process)
|
Detection assays
|
|
ITGA5 (human)
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|
Induces
|
|
|
co-immunoprecipitation
|
|
