Curated Information
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Curated Information Page
PubMed Id: 19524539 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Yannay-Cohen N, et al. (2009) LysRS serves as a key signaling molecule in the immune response by regulating gene expression. Mol Cell 34, 603-11 19524539
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S207-p - KARS (human)
Orthologous residues
KARS (human): S207‑p, KARS iso2 (human): S235‑p, KARS (mouse): S205‑p, KARS iso3 (mouse): S234‑p, KARS (rat): S236‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  RBL-2H3 (basophil)
 Species studied:  rat
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE ERK1 (human)
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
U0126 decrease
PD98059 decrease
Downstream Regulation
 Effect of modification (function):  enzymatic activity, induced, intracellular localization


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