Curated Information

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Curated Information Page

PubMed Id: 16648854

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Gupta N, et al. (2006) Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics. Nat Immunol 7, 625-33 16648854

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

T567-p - ezrin (human)

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Orthologous residues

ezrin (human): T567‑p, ezrin (mouse): T567‑p, ezrin (rat): T567‑p

Characterization

Methods used to characterize site in vivo: mutation of modification site, phospho-antibody

Relevant cell lines - cell types - tissues: B lymphocyte-spleen [ezrin (human)], RAMOS (B lymphocyte) [ezrin (human)]

Cellular systems studied: cell lines, primary cells

Species studied: human, mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
anti-IgM				decrease

T567-p - ezrin (mouse)

▲

Orthologous residues

ezrin (human): T567‑p, ezrin (mouse): T567‑p, ezrin (rat): T567‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Relevant cell lines - cell types - tissues: B lymphocyte-spleen

Cellular systems studied: primary cells

Species studied: mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
anti-IgM				decrease

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