Curated Information

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Curated Information Page

PubMed Id: 12588979

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Zheng L, et al. (2003) Phosphorylation of stem-loop binding protein (SLBP) on two threonines triggers degradation of SLBP, the sole cell cycle-regulated factor required for regulation of histone mRNA processing, at the end of S phase. Mol Cell Biol 23, 1590-601 12588979

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

T61-p - SLBP (human)

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Orthologous residues

SLBP (human): T61‑p, SLBP (mouse): T61‑p, SLBP (rat): T61‑p

Characterization

Methods used to characterize site in vivo: mass spectrometry, mutation of modification site

Relevant cell lines - cell types - tissues: HeLa (cervical)

Cellular systems studied: cell lines

Species studied: human

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
MG132				increase

Downstream Regulation

Effect of modification (function): protein degradation

Comments: required for rapid SLBP degradation at the end of S phase

T62-p - SLBP (human)

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