Curated Information
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Curated Information Page
PubMed Id: 10942766 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Escargueil AE, et al. (2000) Mitotic phosphorylation of DNA topoisomerase II alpha by protein kinase CK2 creates the MPM-2 phosphoepitope on Ser-1469. J Biol Chem 275, 34710-8 10942766
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S1469-p - TOP2A (human)
Orthologous residues
TOP2A (human): S1469‑p, TOP2A iso2 (human): S1495‑p, TOP2A (mouse): S1465‑p, TOP2A (rat): S1465‑p
Characterization
 Methods used to characterize site in vivo phospho-antibody
 Relevant cell lines - cell types - tissues:  HeLa (cervical)
 Cellular systems studied:  cell lines
 Species studied:  human
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CK2A1 (human)


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