Curated Information
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Curated Information Page
PubMed Id: 9686569 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
le Gouvello S, Manceau V, Sobel A (1998) Serine 16 of stathmin as a cytosolic target for Ca2+/calmodulin-dependent kinase II after CD2 triggering of human T lymphocytes. J Immunol 161, 1113-22 9686569
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S16-p - STMN1 (human)
Orthologous residues
STMN1 (human): S16‑p, STMN1 (mouse): S16‑p, STMN1 (rat): S16‑p, STMN1 (chicken): S16‑p
Characterization
 Methods used to characterize site in vivo phosphopeptide mapping, western blotting
 Relevant cell lines - cell types - tissues:  Jurkat (T lymphocyte)
 Cellular systems studied:  cell lines
 Species studied:  human
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CAMK2B (human)
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
anti-CD2 increase
okadaic acid increase
anti-CD28 increase
phorbol ester increase
A23187 increase

S25-p - STMN1 (human)
Orthologous residues
STMN1 (human): S25‑p, STMN1 (mouse): S25‑p, STMN1 (rat): S25‑p, STMN1 (chicken): G25‑p
Characterization
 Methods used to characterize site in vivo phosphopeptide mapping, western blotting
 Relevant cell lines - cell types - tissues:  Jurkat (T lymphocyte)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
anti-CD2 increase
okadaic acid increase
anti-CD28 increase
phorbol ester increase
A23187 increase
anti-CD3 increase

S38-p - STMN1 (human)
Orthologous residues
STMN1 (human): S38‑p, STMN1 (mouse): S38‑p, STMN1 (rat): S38‑p, STMN1 (chicken): S38‑p
Characterization
 Methods used to characterize site in vivo phosphopeptide mapping, western blotting
 Relevant cell lines - cell types - tissues:  Jurkat (T lymphocyte)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
anti-CD2 increase
okadaic acid increase
anti-CD28 increase
phorbol ester increase
A23187 increase
anti-CD3 increase

S63-p - STMN1 (human)
Orthologous residues
STMN1 (human): S63‑p, STMN1 (mouse): S63‑p, STMN1 (rat): S63‑p, STMN1 (chicken): S63‑p
Characterization
 Methods used to characterize site in vivo phosphopeptide mapping, western blotting
 Relevant cell lines - cell types - tissues:  Jurkat (T lymphocyte)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
anti-CD2 increase
okadaic acid increase


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