Curated Information

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Curated Information Page

PubMed Id: 18614800

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Information from this record has been curated, but not yet edited in PhosphoSitePlus^® and may be incomplete.

Wylie SR, Chantler PD (2008) Myosin IIC: a third molecular motor driving neuronal dynamics. Mol Biol Cell 19, 3956-68 18614800

Y118-p - PXN (mouse)

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Orthologous residues

PXN (human): Y118‑p, PXN iso2 (human): Y118‑p, PXN iso3 (human): Y118‑p, PXN iso6 (human): Y125‑p, PXN (mouse): Y118‑p, PXN iso2 (mouse): Y118‑p, PXN (rat): Y118‑p, PXN (chicken): Y118‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody

Disease tissue studied: neuroblastoma

Relevant cell lines - cell types - tissues: Neuro-2A (neuron)

Cellular systems studied: cell lines

Species studied: mouse

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Effect	Notes
siRNA	decrease	immunofluorescence, antisense myosin IIA
siRNA	no change compared to control	immunofluorescence, antisense myosin IIB
siRNA	decrease	immunofluorescence, antisense myosin IIA

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