Curated Information
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Curated Information Page
PubMed Id: 7596441 
Wang Y, Prives C (1995) Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature 376, 88-91 7596441
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
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S315-p - p53 (human)
Orthologous residues
p53 (human): S315‑p, p53 (mouse): S309‑p, p53 iso2 (mouse): S312‑p, p53 (rat): S313‑p, p53 (rabbit): S313‑p, p53 (monkey): S315‑p
Characterization
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK2 (human)
KINASE CDK1 (human)
Downstream Regulation
 Effect of modification (function):  molecular association, regulation, protein conformation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
DNA Induces EMSA


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