Curated Information

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PubMed Id: 8824278

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Information from this record has been curated, but not yet edited in PhosphoSitePlus^® and may be incomplete.

Nebl G, Meuer SC, Samstag Y (1996) Dephosphorylation of serine 3 regulates nuclear translocation of cofilin. J Biol Chem 271, 26276-80 8824278

S3-p - cofilin 1 (human)

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Orthologous residues

cofilin 1 (human): S3‑p, cofilin 1 (mouse): S3‑p, cofilin 1 (rat): S3‑p, cofilin 1 (pig): S3‑p

Characterization

Methods used to characterize site in vivo: mutation of modification site, phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: 3T3 (fibroblast)

Cellular systems studied: cell lines

Species studied: mouse

Downstream Regulation

Effect of modification (function): intracellular localization

Comments: Unphosphorylated cofilin accumulates within the nucleus.

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