Curated Information
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Curated Information Page
PubMed Id: 19410646 
Luo Y, et al. (2009) Novel phosphotyrosine targets of FGFR2IIIb signaling. Cell Signal 21, 1370-8 19410646
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
Download Sites

Y389-p - BDP1 (human)
Orthologous residues
BDP1 (human): Y389‑p, BDP1 (mouse): Y381‑p, BDP1 (rat): Y381‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y15-p - CDK2 (human)
Orthologous residues
CDK2 (human): Y15‑p, CDK2 (mouse): Y15‑p, CDK2 (rat): Y15‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y673-p - DLG3 (human)
Orthologous residues
DLG3 (human): Y673‑p, DLG3 iso2 (human): Y368‑p, DLG3 (mouse): Y705‑p, DLG3 iso3 (mouse): Y368‑p, DLG3 (rat): Y705‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y548-p - DNAJC2 (human)
Orthologous residues
DNAJC2 (human): Y548‑p, DNAJC2 (mouse): C548‑p, DNAJC2 (rat): C548‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y94-p - emerin (human)
Orthologous residues
emerin (human): Y94‑p, emerin (mouse): Y95‑p, emerin (rat): Y95‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y187-p - ERK2 (human)
Orthologous residues
ERK2 (human): Y187‑p, ERK2 (mouse): Y185‑p, ERK2 (rat): Y185‑p, ERK2 (chicken): Y195‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

S347-p - FGFR2 (human)
Orthologous residues
FGFR2 (human): S347‑p, FGFR2 (mouse): S347‑p, FGFR2 iso2 (mouse): Y230‑p, FGFR2 (rat): Y364‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y466-p - FGFR2 (human)
Orthologous residues
FGFR2 (human): Y466‑p, FGFR2 (mouse): Y466‑p, FGFR2 iso2 (mouse): Y352‑p, FGFR2 (rat): Y486‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y586-p - FGFR2 (human)
Orthologous residues
FGFR2 (human): Y586‑p, FGFR2 (mouse): Y586‑p, FGFR2 iso2 (mouse): Y472‑p, FGFR2 (rat): Y606‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y588-p - FGFR2 (human)
Orthologous residues
FGFR2 (human): Y588‑p, FGFR2 (mouse): Y588‑p, FGFR2 iso2 (mouse): Y474‑p, FGFR2 (rat): Y608‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y656-p - FGFR2 (human)
Orthologous residues
FGFR2 (human): Y656‑p, FGFR2 (mouse): Y656‑p, FGFR2 iso2 (mouse): Y542‑p, FGFR2 (rat): Y676‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y657-p - FGFR2 (human)
Orthologous residues
FGFR2 (human): Y657‑p, FGFR2 (mouse): Y657‑p, FGFR2 iso2 (mouse): Y543‑p, FGFR2 (rat): Y677‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y921-p - IRS4 (human)
Orthologous residues
IRS4 (human): Y921‑p, IRS4 (mouse): Y894‑p, IRS4 (rat): Y903‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y40-p - LAMTOR1 (human)
Orthologous residues
LAMTOR1 (human): Y40‑p, LAMTOR1 (mouse): Y40‑p, LAMTOR1 (rat): Y40‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y17-p - PDAP1 (human)
Orthologous residues
PDAP1 (human): Y17‑p, PDAP1 (mouse): Y17‑p, PDAP1 (rat): Y17‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y986-p - SHIP-2 (human)
Orthologous residues
SHIP‑2 (human): Y986‑p, SHIP‑2 (mouse): Y987‑p, SHIP‑2 (rat): Y987‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y62-p - SHP-2 (human)
Orthologous residues
SHP‑2 (human): Y62‑p, SHP‑2 iso2 (human): Y62‑p, SHP‑2 (mouse): Y62‑p, SHP‑2 (rat): Y62‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y351-p - TMPO (human)
Orthologous residues
TMPO (human): Y351‑p, TMPO iso2 (human): Y242‑p, TMPO iso6 (human): , TMPO (mouse): Y350‑p, TMPO iso6 (mouse): , TMPO (rat): Y350‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase

Y306-p - ZNF598 (human)
Orthologous residues
ZNF598 (human): Y306‑p, ZNF598 iso2 (human): Y306‑p, ZNF598 (mouse): Y304‑p, ZNF598 iso3 (mouse): Y304‑p, ZNF598 (rat): Y303‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
FGF7 increase


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