Curated Information
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Curated Information Page
PubMed Id: 9271428 
Larsson N, et al. (1997) Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis. Mol Cell Biol 17, 5530-9 9271428
This page summarizes selected information from the record referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S16-p - STMN1 (human)
Orthologous residues
STMN1 (human): S16‑p, STMN1 (mouse): S16‑p, STMN1 (rat): S16‑p, STMN1 (chicken): S16‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  K562 (erythroid)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Effect of modification (function):  activity, inhibited
 Comments:  regulates STMN1 activity during mitosis

S25-p - STMN1 (human)
Orthologous residues
STMN1 (human): S25‑p, STMN1 (mouse): S25‑p, STMN1 (rat): S25‑p, STMN1 (chicken): G25‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  K562 (erythroid)
 Cellular systems studied:  cell lines
 Species studied:  human
 Comments:  required for phosphorylation of S15 and S62
Downstream Regulation
 Effect of modification (function):  activity, inhibited
 Comments:  regulates STMN1 activity during mitosis

S38-p - STMN1 (human)
Orthologous residues
STMN1 (human): S38‑p, STMN1 (mouse): S38‑p, STMN1 (rat): S38‑p, STMN1 (chicken): S38‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  K562 (erythroid)
 Cellular systems studied:  cell lines
 Species studied:  human
 Comments:  required for phosphorylation of S15 and S62
Downstream Regulation
 Effect of modification (function):  activity, inhibited
 Comments:  regulates STMN1 activity during mitosis

S63-p - STMN1 (human)
Orthologous residues
STMN1 (human): S63‑p, STMN1 (mouse): S63‑p, STMN1 (rat): S63‑p, STMN1 (chicken): S63‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site
 Relevant cell lines - cell types - tissues:  K562 (erythroid)
 Cellular systems studied:  cell lines
 Species studied:  human
Downstream Regulation
 Effect of modification (function):  activity, inhibited
 Comments:  regulates STMN1 activity during mitosis


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