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Orthologous residues
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PAK1 (human): T212‑p, PAK1 (mouse): T212‑p, PAK1 (rat): T211‑p
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Characterization
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Methods used to characterize site in vivo:
[32P] bio-synthetic labeling, mutation of modification site, phospho-antibody
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Relevant cell lines - cell types - tissues:
3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout], S2-6
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Cellular systems studied:
cell lines
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Species studied:
mouse
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Enzymes shown to modify site in vitro:
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Downstream Regulation
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Effect of modification (function):
molecular association, regulation
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Effect of modification (process):
cell motility, altered
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