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Orthologous residues
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perilipin (human): S497‑p, perilipin (mouse): S492‑p, perilipin (rat): S492‑p
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Characterization
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Methods used to characterize site in vivo:
mutation of modification site
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Relevant cell lines - cell types - tissues:
3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout]
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Cellular systems studied:
cell lines
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Species studied:
mouse
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Upstream Regulation
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Potential in vivo enzymes for site:
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Type
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Enzyme
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Evidence
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Notes
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KINASE
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PKACa (human)
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phospho-motif antibody
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Downstream Regulation
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Effect of modification (function):
activation
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Comments:
phosphorylation of site facilitates lipolysis of lipid droplets.
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