Curated Information
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Curated Information Page
PubMed Id: 9122166 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Kwon YG, et al. (1997) Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proc Natl Acad Sci U S A 94, 2168-73 9122166
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T320-p - PPP1CA (mouse)
Orthologous residues
PPP1CA (human): T320‑p, PPP1CA (mouse): T320‑p, PPP1CA (rat): T320‑p, PPP1CA (rabbit): T320‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody
 Relevant cell lines - cell types - tissues:  3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout], SF9
 Cellular systems studied:  cell lines
 Species studied:  insect, mouse
 Enzymes shown to modify site in vitro
Type Enzyme
KINASE CDK1 (mouse)
Upstream Regulation
 Potential in vivo enzymes for site: 
Type Enzyme Evidence Notes
KINASE CDK1 (mouse) pharmacological inhibitor of upstream enzyme
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
olomoucine decrease
calyculin A increase
calyculin A, olomoucine increase
Downstream Regulation
 Effect of modification (function):  intracellular localization


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