Curated Information
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Curated Information Page
PubMed Id: 19291697 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Barberis L, et al. (2009) Leukocyte transmigration is modulated by chemokine-mediated PI3Kgamma-dependent phosphorylation of vimentin. Eur J Immunol 39, 1136-46 19291697
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S5-p - Vimentin (human)
Orthologous residues
Vimentin (human): S5‑p, Vimentin (mouse): S5‑p, Vimentin (rat): S5‑p, Vimentin (hamster): S5‑p, Vimentin (cow): S5‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  macrophage-bone marrow
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (process):  cell motility, altered

S7-p - Vimentin (human)
Orthologous residues
Vimentin (human): S7‑p, Vimentin (mouse): S7‑p, Vimentin (rat): S7‑p, Vimentin (hamster): S7‑p, Vimentin (cow): S7‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  macrophage-bone marrow
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Upstream Regulation
 Treatments, proteins and their effect on site modification: 
Treatments Referenced Treatments Manipulated Protein Referenced Protein Effect Notes
PIK3CG (human) increase
Downstream Regulation
 Effect of modification (process):  cell motility, altered

S8-p - Vimentin (human)
Orthologous residues
Vimentin (human): S8‑p, Vimentin (mouse): S8‑p, Vimentin (rat): S8‑p, Vimentin (hamster): S8‑p, Vimentin (cow): S8‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  macrophage-bone marrow
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (process):  cell motility, altered

S9-p - Vimentin (human)
Orthologous residues
Vimentin (human): S9‑p, Vimentin (mouse): S9‑p, Vimentin (rat): S9‑p, Vimentin (hamster): S9‑p, Vimentin (cow): S9‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  macrophage-bone marrow
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (process):  cell motility, altered

S10-p - Vimentin (human)
Orthologous residues
Vimentin (human): S10‑p, Vimentin (mouse): S10‑p, Vimentin (rat): S10‑p, Vimentin (hamster): S10‑p, Vimentin (cow): S10‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  macrophage-bone marrow
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (process):  cell motility, altered

S39-p - Vimentin (human)
Orthologous residues
Vimentin (human): S39‑p, Vimentin (mouse): S39‑p, Vimentin (rat): S39‑p, Vimentin (hamster): S39‑p, Vimentin (cow): S39‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  macrophage-bone marrow
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse
Downstream Regulation
 Effect of modification (process):  cell motility, altered

S73-p - Vimentin (human)
Orthologous residues
Vimentin (human): S73‑p, Vimentin (mouse): S73‑p, Vimentin (rat): S73‑p, Vimentin (hamster): S72‑p, Vimentin (cow): G73‑p
Characterization
 Methods used to characterize site in vivo mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  macrophage-bone marrow
 Cellular systems studied:  primary cultured cells
 Species studied:  mouse


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