Curated Information
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Curated Information Page
PubMed Id: 19270731 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Ahmed BA, et al. (2009) The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network. PLoS One 4, e4730 19270731
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
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S611-p - SERT (human) ▲
Orthologous residues
SERT (human): S611‑p, SERT (mouse): S611‑p
Characterization
 Methods used to characterize site in vivo:  immunoprecipitation, mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  CHO (fibroblast)
 Cellular systems studied:  cell lines
 Species studied:  hamster
Downstream Regulation
 Effect of modification (function):  activation, molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
vimentin (human) Disrupts co-immunoprecipitation

T613-p - SERT (human) ▲
Orthologous residues
SERT (human): T613‑p, SERT (mouse): T613‑p
Characterization
 Methods used to characterize site in vivo:  immunoprecipitation, mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  CHO (fibroblast)
 Cellular systems studied:  cell lines
 Species studied:  hamster
Downstream Regulation
 Effect of modification (function):  intracellular localization, molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
vimentin (human) Disrupts co-immunoprecipitation

T616-p - SERT (human) ▲
Orthologous residues
SERT (human): T616‑p, SERT (mouse): T616‑p
Characterization
 Methods used to characterize site in vivo:  immunoprecipitation, mutation of modification site, western blotting
 Relevant cell lines - cell types - tissues:  CHO (fibroblast)
 Cellular systems studied:  cell lines
 Species studied:  hamster
Downstream Regulation
 Effect of modification (function):  intracellular localization, molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
vimentin (human) Disrupts co-immunoprecipitation

S56-p - vimentin (human) ▲
Orthologous residues
vimentin (human): S56‑p, vimentin (mouse): S56‑p, vimentin (rat): S56‑p, vimentin (hamster): S55‑p, vimentin (cow): S56‑p
Characterization
 Methods used to characterize site in vivo:  immunoprecipitation, mutation of modification site, phospho-antibody, western blotting
 Relevant cell lines - cell types - tissues:  CHO (fibroblast), platelet-blood
 Cellular systems studied:  cell lines, primary cells
 Species studied:  hamster, human
Downstream Regulation
 Effect of modification (function):  intracellular localization, molecular association, regulation
 Modification regulates interactions with: 
Interacting molecule Interacting domains Effect Consequences (function) Consequences (process) Detection assays
SERT (human) Induces co-immunoprecipitation


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