Curated Information

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Curated Information Page

PubMed Id: 18252867

This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus^®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus^®, click here.

Peiser M, et al. (2008) Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity. J Leukoc Biol 83, 1118-27 18252867

Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.

S376-p - IRAK1 (human)

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Orthologous residues

IRAK1 (human): S376‑p, IRAK1 iso4 (human): S376‑p, IRAK1 (mouse): S376‑p, IRAK1 (rat): S376‑p

Characterization

Methods used to characterize site in vivo: phospho-antibody, western blotting

Relevant cell lines - cell types - tissues: monocyte

Cellular systems studied: primary cultured cells

Species studied: human

Comments: monocyte derived CD1c+ MoLCs

Upstream Regulation

Treatments, proteins and their effect on site modification:

Treatments	Referenced Treatments	Manipulated Protein	Referenced Protein	Effect	Notes
LPS				no change compared to control
Pam3CSK4				increase
MALP-2				no change compared to control

T387-p - IRAK1 (human)

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