Curated Information
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Curated Information Page
PubMed Id: 16262601 
This page summarizes selected information from the article referenced above and curated into PhosphoSitePlus®, a comprehensive online resource for the study of protein post-translational modifications (NAR, 2012,40:D261-70). To learn more about the scope of PhosphoSitePlus®, click here.
Cao H, et al. (2006) Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem J 394, 285-97 16262601
Only sites from this record are displayed on this page. Click on the protein name to open the protein page, and on the RSD number to open the site page. For the complete dataset, click the download button, on the right.
Download Sites

S12-p - TTP (human)
Orthologous residues
TTP (human): S12‑p, TTP (mouse): S12‑p, TTP (rat): S12‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S21-p - TTP (human)
Orthologous residues
TTP (human): S21‑p, TTP (mouse): S19‑p, TTP (rat): P19‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S41-p - TTP (human)
Orthologous residues
TTP (human): S41‑p, TTP (mouse): N34‑p, TTP (rat): N34‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S43-p - TTP (human)
Orthologous residues
TTP (human): S43‑p, TTP (mouse): , TTP (rat): S36‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S46-p - TTP (human)
Orthologous residues
TTP (human): S46‑p, TTP (mouse): I38‑p, TTP (rat): I39‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S48-p - TTP (human)
Orthologous residues
TTP (human): S48‑p, TTP (mouse): S40‑p, TTP (rat): S41‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S66-p - TTP (human)
Orthologous residues
TTP (human): S66‑p, TTP (mouse): S58‑p, TTP (rat): S59‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S88-p - TTP (human)
Orthologous residues
TTP (human): S88‑p, TTP (mouse): S80‑p, TTP (rat): S81‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S90-p - TTP (human)
Orthologous residues
TTP (human): S90‑p, TTP (mouse): S82‑p, TTP (rat): S83‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T92-p - TTP (human)
Orthologous residues
TTP (human): T92‑p, TTP (mouse): T84‑p, TTP (rat): T85‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S93-p - TTP (human)
Orthologous residues
TTP (human): S93‑p, TTP (mouse): S85‑p, TTP (rat): S86‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T95-p - TTP (human)
Orthologous residues
TTP (human): T95‑p, TTP (mouse): T87‑p, TTP (rat): T88‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T106-p - TTP (human)
Orthologous residues
TTP (human): T106‑p, TTP (mouse): T98‑p, TTP (rat): T99‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T111-p - TTP (human)
Orthologous residues
TTP (human): T111‑p, TTP (mouse): T103‑p, TTP (rat): T104‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

Y158-p - TTP (human)
Orthologous residues
TTP (human): Y158‑p, TTP (mouse): Y150‑p, TTP (rat): Y151‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S160-p - TTP (human)
Orthologous residues
TTP (human): S160‑p, TTP (mouse): S152‑p, TTP (rat): S153‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S169-p - TTP (human)
Orthologous residues
TTP (human): S169‑p, TTP (mouse): T161‑p, TTP (rat): T162‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S184-p - TTP (human)
Orthologous residues
TTP (human): S184‑p, TTP (mouse): S176‑p, TTP (rat): S177‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S186-p - TTP (human)
Orthologous residues
TTP (human): S186‑p, TTP (mouse): S178‑p, TTP (rat): S179‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S188-p - TTP (human)
Orthologous residues
TTP (human): S188‑p, TTP (mouse): S180‑p, TTP (rat): S181‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T196-p - TTP (human)
Orthologous residues
TTP (human): T196‑p, TTP (mouse): S188‑p, TTP (rat): T189‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S197-p - TTP (human)
Orthologous residues
TTP (human): S197‑p, TTP (mouse): S189‑p, TTP (rat): S190‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry, mutation of modification site
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S207-p - TTP (human)
Orthologous residues
TTP (human): S207‑p, TTP (mouse): S199‑p, TTP (rat): S200‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S210-p - TTP (human)
Orthologous residues
TTP (human): S210‑p, TTP (mouse): S202‑p, TTP (rat): S203‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S217-p - TTP (human)
Orthologous residues
TTP (human): S217‑p, TTP (mouse): S209‑p, TTP (rat): S210‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S218-p - TTP (human)
Orthologous residues
TTP (human): S218‑p, TTP (mouse): S210‑p, TTP (rat): S211‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry, mutation of modification site
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S228-p - TTP (human)
Orthologous residues
TTP (human): S228‑p, TTP (mouse): S220‑p, TTP (rat): S221‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry, mutation of modification site
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S230-p - TTP (human)
Orthologous residues
TTP (human): S230‑p, TTP (mouse): S222‑p, TTP (rat): S223‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S233-p - TTP (human)
Orthologous residues
TTP (human): S233‑p, TTP (mouse): S225‑p, TTP (rat): S226‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T238-p - TTP (human)
Orthologous residues
TTP (human): T238‑p, TTP (mouse): T230‑p, TTP (rat): T231‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S252-p - TTP (human)
Orthologous residues
TTP (human): S252‑p, TTP (mouse): S244‑p, TTP (rat): S245‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T257-p - TTP (human)
Orthologous residues
TTP (human): T257‑p, TTP (mouse): T250‑p, TTP (rat): T251‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

T271-p - TTP (human)
Orthologous residues
TTP (human): T271‑p, TTP (mouse): S264‑p, TTP (rat): S265‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S273-p - TTP (human)
Orthologous residues
TTP (human): S273‑p, TTP (mouse): S266‑p, TTP (rat): S267‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S276-p - TTP (human)
Orthologous residues
TTP (human): S276‑p, TTP (mouse): S269‑p, TTP (rat): S270‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S279-p - TTP (human)
Orthologous residues
TTP (human): S279‑p, TTP (mouse): S272‑p, TTP (rat): S273‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

Y284-p - TTP (human)
Orthologous residues
TTP (human): Y284‑p, TTP (mouse): Y277‑p, TTP (rat): Y278‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S294-p - TTP (human)
Orthologous residues
TTP (human): S294‑p, TTP (mouse): S287‑p, TTP (rat): S288‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human

S296-p - TTP (human)
Orthologous residues
TTP (human): S296‑p, TTP (mouse): S289‑p, TTP (rat): S290‑p
Characterization
 Methods used to characterize site in vivo mass spectrometry
 Relevant cell lines - cell types - tissues:  293 (epithelial)
 Cellular systems studied:  cell lines
 Species studied:  human


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